LGD-4033 is a brand new selective androgen receptor modulator originally discovered by Ligand Pharmaceuticals and currently under development by Viking Therapeutics.
Originally designed to treat muscle wasting, it was discovered that LGD has exceptional muscle building properties when trialled in healthy adults, amazingly with no evidence of any adverse side effects at all.
Due to its tissue-selective mechanism of action, LGD is capable of producing the same overall benefits of testosterone without the added side effects that come with it.
Effectively, as with most SARMS, the goal of research and developments into this area is to allow a customised response, so that tissues that are targeted will respond as they would to testosterone.
LGD is said to be the pinnacle of years of research and is a non-steroidal oral product that binds with Androgen Receptors which produces steroid-like results without the side effects.
In terms of strength and size gains based off known evidence, LGD is by far the strongest and most effective SARM for these results.
We often here a lot about this SARM as the latest ‘up and comer‘ in the SARMS family with astonishing results but in terms of what makes this compound so great we have built out a quick list covering all the usual questions on benefits we get including:
More specifically if we are to delve into the scientific mentioned above…
Anabolic simply refers to anabolism. Anabolism is the chemical reactions that synthesize molecules in metabolism. By speeding up this process, science has shown a rapid increase in strength and performance in subjects.
The anabolic process essentially strengthens and restructures molecules in order for them to become larger and more efficient.
As LGD binds to the androgen receptors of muscle and bone specifically, it creates enhanced anabolic activity in the body (muscle building) whilst also showing anti-catabolic (muscle wasting) activity.
Androgens are one of the primary sex hormones of the steroidal family. Testosterone is the primary androgen of the greatest importance.
Unlike anabolic steroids that promote large amounts of androgenic activity, the related negative effects attributable to steroids appear to be absent from all documented cases of use as it pertains to LGD. A big plus for those wanting minimal side effects.
Despite an attachment to the androgen receptors, the target area remains muscle and bone. Acne and hair loss cannot occur with this SARM.
The side effects of LGD should also not be concerning to the prostate; some activity in the prostate may exist, but should be insignificant.
The side effects of LGD do not include any of an estrogenic nature, making water retention, bloating, gyno and high blood pressure associated with water retention impossible.
A great result for those looking to avoid these drawbacks.
No negative effects on the cardiovascular system have been reported, such as negative effects on cholesterol or blood pressure.
Minimal side effects
The side effects of LGD appear to be minimal and often non-existent in many users. Unlike anabolic steroids that promote large amounts of androgenic activity, such related negative effects appear to be absent in most all cases. Side effects of LGD are possible, but again very rare, making it one of the more desirable items in the performance enhancement arsenal.
Mild to minimal testosterone suppression
Testosterone suppression is possible but should not be as significant as suppression related to anabolic steroid use. The easiest way to mitigate this side effect is with a steady course of PCT to ensure levels normalise after a cycle. Normalisation of these levels is usually faster and occurs sooner than with the use of other products including anabolic steroids.
Can stack with anything
They great thing about LGD from an overall performance enhancement perspective is that it can be stacked with anything to achieve the desired results. As with most desired results and outcomes we see athletes aiming for multiple sub-categories including:
As this pertains to LGD, these results can be achieved via a number of stacks including…
Bulking: Stacked with RAD-140 or MK-677, LGD can show exceptional bulking capabilities and results.
Fat Loss / Shredding: Combined with S4, LGD can show exceptional shredding capabilities and results.
Lean Gains and Fat Loss: When run simply and a strict diet and cardio overlay to the usual bulk weight training regime, LGD has shown exceptional combined recomping capabilities.
Injury repair: Combined with MK-2866, LGD can show exceptional injury repair capabilities and results.
Anabolic stacking: When stacked with traditional anabolic products, LGD can add lean muscle gains and strength without additional side effects.
In summary LGD is perhaps one of the most exciting breakthroughs in muscle pharmacology and a product that has the sports research world in awe. It indeed has a promising future ahead and one that athletes and practitioners all over the world will be following with anticipation!
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