Description
DESCRIPTION
Product name: Pegylated Mechano-Growth Factor
Short name: PEG-MGF
Concentration: 2mg
Volume: 3ml vial
Suggested Diluent: Bacteriostatic water
Molecular Formula: C121H200N42039
Product Summary:
PEG-MGF Overview
Pegylated Mechano-growth factor (PEG-MGF) is a slightly altered form of insulin-like growth factor 1 (IGF-1). Research shows that it stimulates muscle cell proliferation and differentiation. It has also been explored in research focused on increasing endurance, boosting the function of the immune system, lowering cholesterol, and reducing total body fat. There is also some evidence to suggest that PEG-MGF improves immune function related to healing.
Pegylation is a process of attaching polyethylene glycol to another chemical compound. It
is often done to reduce the body’s natural immune reaction to an agent or, as in the case of PEG-MGF, to increase the half-life of the compound in the blood by reducing clearance in the kidneys. Pegylation is common, safe, and has a number of advantages. PEG-MGF was developed because MGF has a very short half-life in blood. Though it persists for longer periods of time in muscle tissue, MGF administered exogenously has a short half- life because it passes through the blood stream first unless it is injected directly into muscle tissue. PEG-MGF helps to offset this particular disadvantage.
PEG-MGF and Skeletal Muscle
Recent studies indicate that MGF stimulates the insulin-like growth factor 1 receptor just as much as IGF-1. Stimulation of this receptor has been linked to decreased aging, increased lean body mass, and improved energy homeostasis in humans. This function suggests that PEG- MGF can produce effects similar to IGF-1 leading to improved muscle repair, enhanced fat metabolism, and overall increases in lean body mass.
PEG-MGF is also being studied for applications in Heart Muscle Repair, Bone Repair and Growth – and even for its Potential Neuroprotective Effects.
Dosage:
PEG-MGF is sold in vials containing 2MG of lyophilised powder which should be stored under refrigeration. (It is acceptable however for them to be mailed unrefrigerated). The contents can be reconstituted by adding a convenient amount of bacteriostatic water.
For example:
2mg of powder
2ml of bacteriostatic water equals 1000 mcg/ml,
At time of dosing, an insulin syringe is used to draw and then inject the desired amount. In the above example a 100mcg (or 0.1mg) dose would require 0.05mL, or “5 IU” as marked on an insulin syringe.
The general recommended dosage for PEG-MGF is 150 mcg, once a day. And generally, 2 – 3 times in a week, for as long as 8 – 10 weeks.
The vial of PEG MGF should be injected subcutaneously or intramuscularly in the area that needs to be targeted to ensure localized delivery.
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